Mod order is playset / Arrangement after Mod Conflicts.

Something in the Galaxy Species window is causing the GPU to run at minimum clock.
Use the Irony Mod Manager.
https://github.com/bcssov/IronyModManager/releases/tag/v1.20.46

Tutorial:
https://www.youtube.com/watch?v=98dKbDxtqQw

Important When a mod is updated by the creator, you have to delete the old compressed mod & recompress it new. The easiest way is to delete the compressed playset & recompress it. After a mod update, the Paradox Launcher must be started once so that the Mod Manager can recognize new mods. After the launcher has finished loading, you can close it & open the Mod Manager.
EDIT: I also have to start the launcher 2x more often so that it has accepted new or changed mods.

For this playset.
In the Mod Manager, use exactly the same order as in the collection when you create a playset there. Then Merge & Compress. After that click Apply & Start Game.

"Real Space - Star Cluster" is Optional. Since it prevents other galaxy generation types from being selected.

An artifact from some mod is buged. But it doesn't really bother, apart from the fact that it takes up space.

Since the update, there could be errors. I have not checked if all mods have already been updated.
Empires Expanded (formerly Civics Expanded+) e.g. has often caused problems because a lot was changed there in the last 3.3 patch. It has already been updated, but might contain forgotten values. But for me the mod is indispensable :D

The most important mods themselves are all so far up to date. If some mod is not up to date, usually work anyway.