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Much more useful on Hardcore, admittedly.
It gives you hit points back like eating even in regular mode.
The flask is light weight requiring little room in inventory as well.
You paid for the DLC use it.
There is an achievement for playing hardcore and it is a bit more challenging; you can also lose your companions if they're killed forcing you to think strategically. Many prefer not to play the mode, but eventially you will be good enough andyou did pay for the game so get your mileage out of it. Hardcore was the way I first played NV before any DLC was available and made it through so there is no reason not to with GRA and Courier's Stash.
Fabricating and dissemenating auto-injector stimpaks to your companions will help keep them alive allot longer in addition to choosing your battles more wisely; go after the weaker enemies then team up on the stronger ones, isolate, divide and conquer - natural selection is an excellent weapon - all battles are won first through reasoning.
Enjoy!