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Or use stealthboys.
As the other poster said, kill Joe Cobb for his stealthboy and crack the safe in the schoolhouse. Four minutes of invisibility might help a lot.
Go to Scorpian Gulch. There are Radscorpians there, but don't go through the gulch toward Novac yet. Instead, jump on to the cliff where the scorpians can't reach you, and start shooting them from there. I've managed to get to Vegas early easy this way. If the scorps run away, you may have to jump down quickly to get them to come back and jump back up.
there are atleast 2 ways there at lvl one without (with a little luck) ever being spotted by anything
Personally I find Deathclaws to be easier than Cazadors because they're not nearly as fast (and they're much bigger targets), and one hit from them doesn't result in a good chunk of your health draining even after you kill them.
But yeah, it's totally possible to deal with them, especially if you can spot them far enough away and keep your distance (stealth helps, as does having someone like Boone along to help spot far-away hostiles, or ED-E to put said hostiles on your compass from a longer distance away). That way you can engage them before they can close with you, or avoid them altogether.
Not saying it's never possible to take them on up close, just that you have to have pretty good gear and a healthy amount of HP and antitoxin to do so without making it dangerous.
What I'm saying is that I sympathize, and yes everyone finds Cazadors to be difficult to deal with at first. Even in power armor they're still annoying pests if they get close (because somehow venom goes through sealed power armor).
radscorps can be taken with a service rifle and AP ammo.
Ideally a Plasma pistol or rifle with decent ammo but if you put the points into guns you put the points into guns. which I'm assuming you did since you are having trouble.
a 9mm SMG will shred cazadores a few shots to their wings with the spread and the thing is probably not much of a threat and its not like it survives many hits from the weapon.
also works on cazadores.
a varmit rifle is only good with jury rigging to repair a decent gun. like a trail carbine or hunting rifle or brush gun.
a hunting rifle with mods and AP ammo is probably your best bet in the long run for armored targets (couldn't find enough 5.56 AP ammo to make it work except in Lonesome road.)
but I used the marksmen carbine (all american) with AP rounds and wasn't super displeased with it.
or you could just use a laser rifle and kill everything from long range or short range. or a tribeam if you need more firepower.
Out of all the suggestions i got, i went with this. Worked first try, thanks.
You can also pick up Cass if you do a quest for her. She does pretty well in combat, but sometimes she'll disappear, or turn agressive, if you enter Vault 22