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If you don't have Comprehension, skill book + skill magazine gives you 13 points. A followers lab coat gives you 10 points. Now you're two points short, which can again be covered by Mentats, if your INT allows.
The DLC adds some additional quite effective options:
With a high survival skill, black coffee from Honest Hearts can also be a big help as the effect scales with survival. At 100 survival you can get a whopping 12 points from the temporary 6 INT bonus.
The scrubs from the doctors in OWB also provide a decent bonus as they boost both science and INT. The range here is 10-19 points, depending on your INT.
Check the science page on the wiki for more.