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one you hit level 30 and have a good supply of chems and fixer, remove it with the autodoc.
the early part of the game is the difficult part.
It's there purely to gimp your character so that you can't just max out most of your skills and get a stupid number of perks making your endgame character less of a "jack of all trades master of all".
Yes. It is worth it. It's the strongest trait in the game by far. You don't even need to remove it in the autodoc if you want it, although it is recommended. Buy all the med-x and you'll basically have a power armor plus your regular armor at all times, and that is only one drug.
I'll let you think about all the others.
Lethal force engaged.
and getting rid of the side effects of the cems also cost literally nothing.
That's my point. Junkie build is one of many valid options to play the game hardcore-style, and logan loophole is hands-down the best trait since it turns the early game into a kid's party.
at this point it would be better just take the chem resistant perk and spamm drugs all day, and even if the character gets adicted somehow, the cost for the doctors help is like pocket money, and also the player can buy/find fixer all over in the world.
i never seen any point of this logan hole trait, its just screwing the player character up for a positive effect that can be gained with little to no effort anyway during the gameplay.
Thing in old world blues that heals you. Can use it to one time swap out your initial traits