Wild cards side bets, what should I do?

[Everune]

I'm at the point where you meet all the factions, and I've just been talking to them and leaving without doing their quests. Is this a mistake? Should I do all of their quests first, or just tell yes man to ignore them?

To be honest, I don't like any of the factions much.
BoS put an explosive collar on my neck.
Omertas are basically mobsters
White gloves are stuck up jerks
Khans are raiders, and I think I might already be their enemy
Boomers are pretty nuts and want to bomb everything, but they might be my best choice.

[smokeylake]

Do what you want. BoS end up terrorizing the mohave if left alone. Yes man suggests they be killed because of their ideology and beliefs of technology. This will effect Veronica if her quest “I could make you care” isn’t completed. Both factions in the strip are terrible people. I don’t want to say why but if you haven’t complete the quest “beyond the beef” and “how little we know”. To really understand. Khans join the legion if left alone. Boomers don’t affect anything other than the ending slide show and the final battle over the dam. It’s all up to you if you care about the ending slideshow.

[Operation Iraqi Freikorps]

You can do quests to influence the endings or just choose to ignore them. Either option works.

[TheSkunkyMonk]

Its all up to you, you can clean up their acts though if you do it right so they arent as bad... Still a bunch of protentious pricks though, I wanted to let the Followers run the show but sadly they didn't give us that option :( was the same in fallout4 I wanted to let synth who was in the brotherhood take over, but sadly on that occassion they actualy removed that part of the story(you can still check some of the audio out though)