Best Relic Of All....

[Ashy]

Ice Cream.

[vepper]

Ice Cream is pretty good, though there's some other big contenders for "best relic" in my eyes. Both "bottled" relics are amazing for consistency (and I hope there's a locked or in-development bottle for Powers, as those would be the best to make Innate) Peace Pipe gives you far more potential for card removal than anything else in the game (if you were lucky to be given it as a st arting relic, you could probably remove at least 5-6 cards, maybe more if you hit many campfires or rarely need to rest), Unceasing Top, though gimmicky, can allow infinite combos in the right decks; Black Star can be insane if gotten early, though is risky to take advantage of, and of all the energy-boosting relics I've seen, the Sozu seems the best; as potions are one of the easier things to sacrifice (if gotten somewhere on level 3, Ectoplasm is even better, as you likely don't need anymore gold regardless), These two are more subjective, and I probably overvalue at least one of them, but Thread and Needle is one of the best defensive relics in the game (a slightly worse Metallicize 5, but having more block makes it easier to preserve Plated Armor), and the Frozen Eye can be very useful in planning out your actions, knowing what you'll draw with draw spells, and knowing when you draw important cards.

[Bullfrog12]

Ice Cream is only useful if you tend to have leftover energy each turn. My favorite Relic is Juzu Bracelet.

[IceCold™]

The one that heals you at rest based on your deck size; You can focus on upgrades; very handy.

[Hotcakes]

Ice cream seems a little too good tbh. Any turn where the enemy doesn't attack you can be used for stockpiling more energy than you'll ever need for the rest of the fight.

[KerZerBer]

We dug it up once and it was the most earthly, sweet release we could ever ask for.

[Xat]

Necronomicon: first attack each turn that costs 2 or more are played twice. This relic singlehandedly won me a run! This relic and whirlwind is a 3 energy 48 damage AOE! Pretty rare though, only got it once thru an event...

[loneknight]

You can only get Necronomicon through an event, yeah, and only randomly as one of the 3 results.

I did some infinite combos with sundial, so it gets a mention.

[Aku]

I think best relic is purely based on your deck at the time as said above.

For example on one of my winning silent runs I had ~6-8 powers and the Mummified Hand (random card costs 0 after using a power) creating a TON of combo/chains that would never be possible otherwise. Sure I had a ton of other relics but the synergy from the hand was the most noticable by far.

[PadainFain]

Just had an Ice Cream + Pyramid + Bandages with a high discard/draw deck on The Silent. Entire 2nd and 3rd levels without taking a single point of damage... including The Nemesis, Stabby Hand thingy and TimeKeeper as final boss. The most fun run I've had so far!!

End of Run: https://gyazo.com/52d93e026c620a89b1151f18665405b0

[pop pop]

Shovel
Allows you to get other useful (or not so useful) relics.
You will most likely die from being to greedy.

[BeefJerkyHunter]

Ice Cream is pretty dang good. I always try to buy it at the shop whenever I can. My favorite relic, which I've gotten only once ha, is the First Aid Kit thingy. Exhausting those status cards feels really nice.

[Ashy]

There's also another relic that is great, I forgot the name of it. But it's a tail that heals you back to 50% health when you were supposed to be dead. Can really stop those boss-ending runs.

Too bad it only works once :/

[Pear]

Lizard's Tail. I actually consider it to be one of the worst ones though, unless the deck is beyond saveable I guess and can't use extra energy.

[vepper]

It can be good if the energy artifacts are bad enough and the other stuff being offered is stuff like tiny house, at least. I've been saved by it at least once before, though there are certainly better boss relics

[sf734efb;l4]

I don't know if it counts,but isn't burning blood like the best relic in the game?