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This subject has been discussed to death. There is an active thread ongoing right now.
Gen 1 & 2 are androids of a sort, while Gen 3 are Human or Clone with a mind controlling chip in their heads.
Kellogg is a Cyborg. A Human with with Cybernetic Implants.
Yes, Aachen, they can be called Replicants except they don't self replicate.
Edit: Not really a Clone either since the definition of a Clone is an exact copy. Each Gen 3 looks different but they are made from the same base DNA Structure.
Fallout 3 talks about this in a quest; they have synthetic skin, bones, blood... Plus they can be reprogrammed, formatted or ordered around like your regular Mr Handy.
Well, I was thinking more Nexus-8 or Nexus-9, but I see how apt those Series may be.
"a cybernetic organism: living tissue over a metal endoskeleton"
Also while the skin may appear to be organic, I'm not entirely certain it is. It lacks certain components present within human cells.
When they try and escape and have their mind wiped it is because they cannot live with what they have done. Many settlements wiped out, the capture and use of FEV and other things on humans etc.
So to the topic, while they may not be human they are extremely close. Star Wars and the clone troopers went into this a very little bit as well as other titles. Fallout 4 is an excellent story that goes into this as well.