I'm going to keep this plain & simple based on what I've tested. When I have the overhaul enabled, the biomes are on the opposite sides, even if you use the exact same seed.
For example:
- w/o overhaul, Ice biome, dungeon, & sulpuric sea are on the west. the desert & jungle being on the east.
- WITH overhaul, it's flipped horizontally entirely, the ice biome & dungeon being on the east, and the desert & jungle on the west.

I'm not sure if this is a mod conflict, and/or if anyone else has noticed this, but it is a problem with infernum, as I'm sure at least a few people are aware that the Profaned Garden ALWAYS generates on the east side, regardless of the Brimstone Crags location.

If there is a fix for this, please share, for me, and anyone else who has this problem.