Really large food storage,really large foraging ,really large farming,etc...They cause a large assortment of bugs .Loss of pathing,inability of crops to grow,chain messages about players states (hunger,thirst,wounds,etc..) to name a few.

a reboot of the game can lessen and sometimes stop the bugs,but the only sure way is to remove the area/s.Use the clear option for the area,this stops the bugs without having to reboot the game.