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If you refuse to use wiki, just save before attempting alchemy, so you don't waste the materials.
Unfortunately the game doesn't keep track of the failed combinations that you tried, so even if you make a combo that you've done it before, it will still show as a "?" instead of the resulting alchemy goop.
Recipes that you discover are added to the list and can me done as any other blueprint in the game.
I would also refer to a wiki for the tier 2 recipes. With a 2-combination system it is manageable but still rather dull. I have done this systematically with a beautiful google spreadsheet and reloading to minimize the goo-production, since you have no clue what to do with the goo in any part of the game and burning it (destroy) is no option.
The alchemy system is nothing to "understand" and nothing you can "reason" about. No clues, no hints.Plain nothing. Why would "Alcohol + Slowing Solution" make a White Paint? Or "Health Powder + Chaos Solution = Heal Potion"? To me this looks totally random.
This is a rather lame element in the game which eats up the fun.
TL;DR: google it to keep the fun.
the alchemy system sure is stupid :/
Black Graphite powder + water = black color
then I mixed the white bone powder + water thinking it'll give me white color... O_O
Life/death
Order/chaos
Acceleration/slowness
Health/toxic
The ingredients are
Solutions
Powders
Extracts
When a combo makes a successful potion, it's inverse usually makes the same. I.e, acceleration powder and slowing solution makes the energy elixir, but so will slowing powder and acceleration solution.
Okayyyy I don't know ♥♥♥♥ about this...uhh where'd I put that wiki page again???