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Heroes like Lina Ogre magi and especially earth shaker, need key items to become very effective, or can make much more use of having more items, so you typically run these 4th (or actually core as is often the case). All of these heroes can technically play either spot though.
Unless you are playing at a pretty high skill level I wouldn't sweat it too much as in most pub games there isn't much of a distinction between 4th and 5th.