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You only need to worry about armor reduciton on heroes that actually have armor in most cases. If a guy has high/low hp but next-to-no armor then it really doesnt matter, take advantage of his vulnerabilities and get dmg output to exploit his lack of armor.
Normally let's say, bounty hunter or Lycan core item is Medallion of Courage.. which for lycan good to solo rosh, and kill off same as for bounty, an agility hero or someone with armor.. but if the enemy has 4 squishy, and only 1 armory hero, it would be pointless to get something like Medallion of Courage..
vs Sven for example, that has an armor buff, it would be better to get Diffusal Blade.. it slows him and takes away the buff once he activates it.. the item will give you agi hero both your core stats, slow and that purge buffs or clear negative buffs off yourself.. rendering Medallion of Courage useless
Then again can get someone like Slark, and get a deso on him.. or a hero that uses Desolator.. as long as the team targets the same hero you do, that -7 armor will benefit the whole teamfight
armor is most effective from 0 to 1 (by %)
the valor item (I think thast what its called the cheap one that self lowers) makes sense on anyone who can lower someone's (assuming a 2v2 lane) well think shaman, chicken 1, shackle the other
desolator..underrated on someone like ember spirit (keep in mind he applies it to EVERY opponent during his W..and for a midgame carry that means the late game carry has it easier)
As for casual "solo pub" teams, you will probably be getting -amour items if you are planning to go for an early roshan or early game ganking setup...