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if you get bristel on your lane, first thing to buy is magic wand, great heros to harass him with would be cm with second spell, also if you are a carry and against bb you can buy an blademail and use it when the quills are at 3 or 4, then it will do alot of dmg back att bb, also remember that bristel takes more dmg at the front, he will shoot quills if attacked from the side or behinde, you can always try and bait him to towers and then stun or whatever you have hadd
AA or SS or Skyrath can make it happen as solo supports; other supports can don it to, but usually need help from their pos 4 (this is only for laning stage)
Afterwards you just need a silver edge for him.
Stun to disable and attack him down, but don't chase too much. Try attack from front, not his back.
Mana draining, makes a Bristleback pretty useless.
Magic stick - First item, it will gain charges due to his Qull Spray
Town Portal Scroll - If alone and stacked against, a way to escape being chased down
Silver Edge removes Bristleback's passive, taking away both his tankiness as well as his damage output
Solar Crest reduces Bristleback's armor greatly
Assault Cuirass armor aura reduces the Quill Spray damages a lot