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I'm still not sure how restarting the game didn't fix your issue. Have you tried doing that AND mutating another Varkid pod, or did you just go looking for the piece that already dropped?
Because I've heard that some people got the problem that there was no hint, but they could infect the pods without problems...
The quest is split into two parts, one part being infecting the first pod and killing the hatching varkid. Upon picking up the sample, it switches to the second part, in which you have to mutate, kill and loot 4 more varkids.
Since you never picked up the first sample, you're still stuck there, and apparently can't infect any more pods.
Solutions: Try to come back later, maybe it'll work again (though unlikely)
Join somebody who's doing this quest in Multiplayer to complete it.