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Generally I would advise you stop any digging etc in any nearby slime biomes when you have sick people and think you might get more. This depends on their traits though. Some dupes can dig away in slime all day and basically not get sick, while biohazardous dupes will get sick almost immediately. You need enough sick beds for all the sick dupes, but also enough healthy, non-squeamish dupes to heal them to prevent deaths. I would recommend a door at the exit to the slime that you lock for all the dupes until everyone is healthy again. Then maybe a few exosuits to reduce the problem once you get the tech.
It is also smart to build the medbay sort of close to the kitchen. The malingerers will usually need to go there to get food, which can spread germs. The shorter the distance, the less problems you'll have. You can also have a food supply in the medbay. But I think that can get a little fiddly to keep stocked sometimes, so I just use the mess hall and build the two close to each other. And no ladders if poss. Sick dupes tend to drop food sometimes when they have their animations, and if that's on the ladder it will drop to the basement so they will have to go back for more food. I once had a dupe starve to death because of this.