Finally Got both ranks of chem resistant

[Ellronn]

I am level 51 and have put off taking copious amounts of drugs unless I was resistant to them.
My main question to you all is what's your favorite drug combo in fallout 4 to take

[Knavenformed]

The addictions aren't that bad if you tend to use them
And with Junkies legendary weapons they end up being a massive damage boost only behind low HP stacking, so the best overall

[Death Approaches]

you're not a very inquisitive gamer are you, just carry some addictol and some refreshing beverages, it's a status thing like ammo... no ammo, no shoot / ammo, shoot... addicted, debuff / treated or cured, debuff removed. no 28-day treatment program. you struggled through those early levels for nothing.

you can't get addicted, who cares?! take em all. use a hotkey and mass drug-up all at once, but the 8 (now 16 for you) minute duration combo ones are good for clearlng locations fast, psychobuff, bufftats, etc. but of course you don't need them now, it's just a bonus, you've gotten at least one weapon class to 5* and doing 100% damage and 30% penetration, probably more than one legendary and unique weapon, etc.

when you make your NEXT character, remember to take your anti-drugs with you along with your drugs, because you'll find them a lot more helpful at 5th level than 51st... especially if you go survival, it's almost a requirement unless you enjoy turtling your way across the commonwealth.

[Ðe§er†FoX]

Psycho jet all the way

[Cor.]

Rad Scorpion Egg Omelettes.

[TheNutshaq]

Psychojet gives you bonus damage, damage resistance and slows time. I'll either use power armor or psychojet to take down tough enemies

[Makeithappen]

Originally posted by Knavenformed:

The addictions aren't that bad if you tend to use them
And with Junkies legendary weapons they end up being a massive damage boost only behind low HP stacking, so the best overall

yeah if you go for a junkie build you have insane damage. But you are a glass cannon. It is one way to play the game...

[Shadow]

You gotta love the irony.

Before Chem Resistant: "No way. I'm not taking any chems. I might get addicted to that stuff."

After Chem Resistant: "OH YEAH!!!! BRING IT ON!!! I got enough psycho and jet and all sorts of other chems for three lifetimes and I'm constantly using them all!!! WHOOO!!!"

[Makeithappen]

Some addictions have withdrawal of -10% damage reduction. And if things are calculated additively it would almost negate 1 armor piece that reduces damage by 15%. That is one of the effects you probably don't want to have. Especially if you are not doing some kind of junkie build.

For the most part the effects are minimal and most players will be able to play without really noticing a difference.

However if you don't want to suffer the effects of addiction, addictol or radscorpion omelettes is something you'll want to carry with you.

For chems I like to use psychojet as it is an all around good buff for any situation. damage, defense, slows time and extra AP.
Overdrive is pure damage. And if you spam crits in combat you'll get the most out of it. It lasts for 8 minutes. So something you take before clearing out an area with a lot of enemies. Like Gunner Plaza.

Psychobuff is a great for melee builds.

Bufftats is good for that 3+ strength if you need extra carry weight. If you know you aren't struggling to do damage this is a good alternative to boost your special stats. Otherwise just use a Psycho variant.

I've never used Fury. The +50% damage boost might help if you can get it early on in the game for melee builds. Later on in the game you're probably doing so much damage that you probably won't need it. I can see this being a nice one to have for unarmed builds as they do less damage and have a limited selection of weapons.

[Doombringer]

The only bad addictions are the -10% damage resist ones (Psycho, Med-X).
You can get almost infinite psycho (and jet and buffout) by doing nuka-world and filling a raider base with Pick-Me-Up stations though.

[Cor.]

I just stock up on everything, then mass sell it to vendors for loads of caps

[Ellronn]

What this thread has taught me is that most of you need to enter rehabilitation centers immediately

[SkunkPlaysGames]

Psycho and Med-X. Jet is really useful for running away when things go tits up. You can cover a lot of ground very quickly sprinting on Jet.

[FauxFurry]

Originally posted by Penn (Dark Wizard) Jillette:

What this thread has taught me is that most of you need to enter rehabilitation centers immediately

Are there any good rehab center mods to cure their digital addictions in, perhaps the 128-Bitty Ford Clinic or something to that effect?

[milo29]

Not psychojet alone. It's interesting drug but you lost the jet for near nothing if you use psychojet. Psychojet has jet duration in seconds and psycho duration in minutes.

The psycho do not stack. Then mreferably use one psycho for 8mn duration and take multiple jet separatly.

Use overdrive also. Overdrive give you 25% of critical shots out of the vats and stack with the perk better criticals, also with weapons receivers that increase critical damage or pair that with an automatic weapons to multiply the numbers of critical hit during a jet session.

If you are in survival, taking chems increase your thirst and decrease your intelligence. consequently If you have the perk idiot savant that augment the chance to trigger it for big xp gain.

At high level, when idiot savant trigger on a super mutant boss you can gain 3 or 4 level in one time. Except the leveling is exponential and it become a bit hard to level after level 150. Idiot savant and drugs to decrease your intelligence during fights is absolutely necessary if you wan't reach these levels in a decent time.

[Ellronn]

Originally posted by milo29:

Not psychojet alone. It's interesting drug but you lost the jet for near nothing if you use psychojet. Psychojet has jet duration in seconds and psycho duration in minutes.

The psycho do not stack. Then mreferably use one psycho for 8mn duration and take multiple jet separatly.

Use overdrive also. Overdrive give you 25% of critical shots out of the vats and stack with the perk better criticals, also with weapons receivers that increase critical damage or pair that with an automatic weapons to multiply the numbers of critical hit during a jet session.

If you are in survival, taking chems increase your thirst and decrease your intelligence. consequently If you have the perk idiot savant that augment the chance to trigger it for big xp gain.

At high level, when idiot savant trigger on a super mutant boss you can gain 3 or 4 level in one time. Except the leveling is exponential and it become a bit hard to level after level 150. Idiot savant and drugs to decrease your intelligence during fights is absolutely necessary if you wan't reach these levels in a decent time.

My intelligence in fallout is at like 7 so I'm not sure Idiot savant would necessarily help me