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This
Broadly speaking, yes. Although there is an issue of degree at play. There's some that maintain their original personality and intelligence, like the residents of 118, although there are still some side effects. Those are all cases of people trying to extend their own lives though.
Most robobrains are the result of, well to put it simply, a bunch of amoral scientists and engineers trying to create a new more advanced robot rather than some rich dude trying to live way past his expiration date. Brains carelessly extracted using overworked machines that were never designed or intended for mass production. A personality and memory wipe that had to be re-administered every so often to prevent the brain trying to reassert its old personality. (Which obviously they're not receiving in the post-war wasteland.) Brains taken from violent criminals and various other unwilling subjects.
Also if I remember correctly, early models had some issues with the gel that caused degradation.
And that's before getting into the nitty gritty design flaws, like how they would start overthinking the orders they were being given and try to fulfill them in ways that the controller did not expect nor desire.