Minutemen missions.

[One Eye Jack]

I decided to stick with the Minutemen as long as possible. Do these missions ever come to a conclusion? Or does Preston just keep giving you new missions endlessly?

[Fear2288]

Well, there’s only so many settlements so eventually he’ll run out of settlement-taking ones.

Missions revolving around helping settlements out or defending them are radiant so they’ll just keep going forever.

Each faction has their own assortment of endless radiant quests, but there’s also their main one which eventually ends with destroying the Institute (or destroying the BoS and RR if you side with the Institute).

[One Eye Jack]

Originally posted by Fear2288:

Well, there’s only so many settlements so eventually he’ll run out of settlement-taking ones.

Missions revolving around helping settlements out or defending them are radiant so they’ll just keep going forever.

Each faction has their own assortment of endless radiant quests, but there’s also their main one which eventually ends with destroying the Institute (or destroying the BoS and RR if you side with the Institute).

Ok thanks. Still a few settlements to go I think.

[Sepulchure]

Originally posted by One Eye Jack:

I decided to stick with the Minutemen as long as possible. Do these missions ever come to a conclusion? Or does Preston just keep giving you new missions endlessly?

They go on forever.
Minutemen only have 5-ish missions in their "unique" questline: The start, taking the Castle, unlocking Castle Armory, 1 optional quest, and then the ending.

They are the "last resort" faction.

[Longhaul]

They last until you go up to Preston and hit him in the head with a blast from your Boomstick.

[ssddsquare]

There is one settlement that if you get a quest from Minuteman, it will lock out a side quest from the Institute. So I usually get 3 or 4 from the Minuteman and progress with main story until a delivery quest to a settlement from the Institute before I resume the Minuteman quest.

[One Eye Jack]

Originally posted by ssddsquare:

There is one settlement that if you get a quest from Minuteman, it will lock out a side quest from the Institute. So I usually get 3 or 4 from the Minuteman and progress with main story until a delivery quest to a settlement from the Institute before I resume the Minuteman quest.

Ahh.... I didn't know that. Do you know the settlement?

[Death Approaches]

it's not just the minutemen that can bug it, if you take over Warwick Homestead as a settlement, there's an institute quest that requires the synth in charge being alive to give him some seeds to grow, and you can't without console... don't worry about it, it's a dumb side mission, play as you want, and if you side with the institute and get it, just cheese it along from the console.

the radiant quests never end even even if you can't assist anymore, there are still attacks and kidnappings and nearby ghouls/supermutants/raiders to eradicate that it just resets that target location again, and go on forever...