Weakness: Take +20% Damage

[CPT Schnizleblitz]

I've gotten this a couple times now and I have no idea how. Anybody figure this one out yet?

[cassiels]

I think it is lack of sleep over an extended period of time. I just did Unlikely Valentine and that quest takes a long time. Sleeping on the mattresses to save halfway just adds to the lack of sleep. I had this weakness. Luckily I had 8 Nuka Cola Quantums, so I finished the quest on caffeine.

Edit.
I looked it up on YT. They said weakness comes from going 5 days without eating or drinking. In my case that was not true because I had plenty of food and purified water.

[Eustace the Monk]

I got it after being bitten by a molerat at the USAF Olivia location early in the game.

[Vulture]

I suspect multiple causes
radroaches and other vermin
and I'm pretty sure I got after a buff/medx/psych/jet rampage against some skullies and a legendary when I wasn't wearing PA.

I have C6 and Local LEader 2 just so I can setup med vendors and pay them 15 caps to "Cure ME" in my forward settlements. Have not used antibiotics since I hit lvl 14.

[CPT Schnizleblitz]

Yeah, it's bizzare at the least. I searched for any info on it but, not a lot of solid info on diseases/illnesses yet. I always keep up on my characters needs. I usually get weakness when I'm tinkering around in my settlements. I know I've gotten it from a 1hour sleep save at least once.

Yeah Vulture, I usually get that set up asap but, this is a new playthrough. I've actually found a good ammount of AntiBs this run so I'm holding off till I can build the tier 3 doctor. I built the the level 1 asap my last run. ;)

Some of these diseases and illnesses are probably still in play by the devs so, I guess I'll just have to wait and see how it all pans out.

Good hunting gentelmen.

[cassiels]

Apparently on the Bethesda forums they said that weakness occurs whenever something happens that your body cannot cope with or barely. So yeah, extreme lack of sleep, vermin bites, extreme rads, not eating, overdosing on meds. All that.

[Hellsing]

its also something you can catch from sleeping

[Bored Peon]

Originally posted by sweet lemonberry rainbow:

its also something you can catch from sleeping

Actually sleeping is when illnesses catch up to you. Things you did that day catch up to you when you sleep unless it is an immediate illness caused from damage taken. Even eating certain foods will catch up to you (like parasites and such.)

Think of it like an incubation period and the illness breaks out later.

[CPT Schnizleblitz]

Originally posted by Bored Peon:

Originally posted by sweet lemonberry rainbow:

its also something you can catch from sleeping

Actually sleeping is when illnesses catch up to you. Things you did that day catch up to you when you sleep unless it is an immediate illness caused from damage taken. Even eating certain foods will catch up to you (like parasites and such.)

Think of it like an incubation period and the illness breaks out later.

Ahh that makes sense and is a pretty cool system if that's the case. =)