To anyone using .ESP Explorer - it needs updating and is the cause for your CTD's...

[Ruin]

As per the title, .ESP Explorer is in need of an update and seems to be causing immediate CTD's when active, along with CTD's when loading any save that was saved while it was active (after having disabled it)...

Quick work around I found for the save issue was to disable .ESP Explorer, launch FO4 without F4SE, save your game and exit, launch again this time with F4SE (leaving .ESP Explorer disabled) and save... Everything seems to work as normal then...

For those who don't know what .ESP Explorer is (and are tempted to ask), link below :

http://www.nexusmods.com/fallout4/mods/16718/?