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I think if you give Mamma Murphy enough drugs to get her to tell you about it then it is available to find. Otherwise it does not spawn and you must either pickpocket it from McDonough or get it from his Secretary.
So basically press E on all the chairs to find where the key is, it's maybe just not showing up bc of a bug or something
*** okay so bit of testing.... key absolutely does not spawn unless mama murphy tells you about it. (remembering it from a diff playthrough doesnt count haha) another commenter was correct in that it isnt visible and you just click search on some of the chairs. Mama murphy will not tell you about until you reach the point in the quest that you and nick are going to kelloggs door. She will skip right to her glowing sea advice if you havent reached this point. (it was at giving her med-x point for me.) Given her eventual OD there may be limited hints she can give before her death and id rather have the coarsier shut down code for later. so probably better to use that hint as a last resort? (if you cant pick the lock or bribe anyone.)
i heard that there was a key under there, and i just wanted to see if it would be there, turns out its a great speedrunning strat if you have a low charisma level...