Install Steam
login
|
language
简体中文 (Simplified Chinese)
繁體中文 (Traditional Chinese)
日本語 (Japanese)
한국어 (Korean)
ไทย (Thai)
Български (Bulgarian)
Čeština (Czech)
Dansk (Danish)
Deutsch (German)
Español - España (Spanish - Spain)
Español - Latinoamérica (Spanish - Latin America)
Ελληνικά (Greek)
Français (French)
Italiano (Italian)
Bahasa Indonesia (Indonesian)
Magyar (Hungarian)
Nederlands (Dutch)
Norsk (Norwegian)
Polski (Polish)
Português (Portuguese - Portugal)
Português - Brasil (Portuguese - Brazil)
Română (Romanian)
Русский (Russian)
Suomi (Finnish)
Svenska (Swedish)
Türkçe (Turkish)
Tiếng Việt (Vietnamese)
Українська (Ukrainian)
Report a translation problem
Most weapons are pretty balanced, and at core you generally get one boost for the weapon itself (automatic/pistol/rifle/heavy) and sometimes one additional boost based on some other special effect, like explosive or radiation damage. After that basic start, you've got boosts based on things like melee/ranged (Rooted), suppressed weapons (Mr Sandman), and so on..
If we're talking about which weapon gets the biggest overall boost from adding everything together (rather than which gets a boost from the most sources), it might well be a melee weapon, possibly a Disciples knife, since Mr Sandman gives a much higher sneak attack boost to melee weapons, and Nuka World has some perks that are knife-specific (they say combat knives and switchblades, but as I recall, they also apply to the Disciples knife).
Another unique weapon that hasn't been mentioned yet is the Kiloton radium rifle, which can be bought at the Nucleus in Far Harbour. Like Spray n' Pray, it has the Explosive prefix, but being a radium rifle, it also deals radiation damage, allowing it to have that part of its damage doubled by the Nuclear Physicist perk (though radiation damage isn't the most effective damage type around, due to all the enemies resistant to it).
But as I've found more recently, workbench glitches in the vanilla game can create items that are far more powerful than just an Instigating gauss rifle.
Of course, Bethesda ninja-patched the function for damage, before Explosive weapons used to distribute the total weapon damage as an explosive, so a single shot from an Explosve Advanced Shotgun would do somewhere around 2500. Now, only the 15+(Perks) is explosive, and defanged considerably until Demo Expert 3.
The real damage of the explosive guns now comes from limb overkill. Just like Grenades.
To answer OP's question, the Kiloton Radium Rifle probably ends up the most gun weapon in the game with full spec into its damage.
You can use: Rifleman/Commando + Demolition Expert + Smooth Operator (Suppressed) + Explosive Bobblehead and Nuclear Physicist (Radiation Damage) on it.
In a similar vein, Atom's Judgement ends up being the strongest single-attack weapon in the game, reliably. You can crank more damage with a Berserker's or Instigating Sledge with full Nuka World modifications. But Atom's Judgement is Guaranteed and will probably one-shot everything anyway.