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Increased HP
and
Battle of Stamina or HP Amplification depending on the character. Put Max HP on all your external components (look for double HP rolls).
You should have comfortably 10-18k HP or more depending on the toon. If you get to 10k DEF on top of that, you're doing well, but I don't usually waste slot.
For the bosses ... do SOLO void runs. Even if you don't beat the boss. Try and stay alive as long as you can. Learn the mechanics. Just run around, avoid the mechanics and do damage. For good builds, you should be able to solo everything up to where they stop letting you.
HP Collector is the best mod in the game for most descendants. Don't sleep on it.
I find it more versatile to have baseline Resistances for general PvE content and combining some Shield Recovery in Combat with the general Shield Recovery modifier actually works decently well. Def I know is useless after 50k but pumping it up past a small baseline is definetly noticable as I simply face tank Hard mode bosses attacks with ease.
Maybe ill farm some HP gear and see if it works. I only worry about Intercept bosses since those HP drops can be iffy to rely on.
In normal diff, elemental res isn't needed for any of it. Hard, elemental gets hit as hard as base dmg, but only when dealing with bosses, standard mobs still do almost none. The big elemental dmg hits are avoidable, the not avoidable ones do not much.
1:1, +firearm attack gives more dps. 10% attack = 10% add base dmg, 10% crit = 1% add to base crit, 10% weakpoint = 0.1% add to base weakpoint.
Crit multiples base attack by 2 or 3 depending on if its 1.0 or 2.0. Weakpoint does the same. Hitting a weakpoint with a crit, that is base attack x2-3, crit then multiples that total by 2-3. Elemental dmg never gets multiplied,
So once you max base attack, go for clip size and then reload speed, followed by attack speed. If the clip size is under 10, don't buff clip and goes reload instead. If attack speed is under 100, don't buff that, go reload speed instead. If all are low, find another module for buffing base attack some how ( High-Impact have a gold mod for +100-200% firearm attack for next shot after reload with no negatives )