how many runs to finish the main storyline

[Nat]

okay i have battled out and talked to persephone like 4 or 5 times already and i really want some story resolution when does that actually come

[Suzaku]

10 for the first ending. Like 50+ more for the full ending.

[The Sojourner]

Originally posted by Suzaku:

10 for the first ending. Like 50+ more for the full ending.

This. I've also been doing some experimenting, and it can take less than 90-100 runs to fulfill all the prophecies on the Fated List (likely more if this is your first playthrough and/or if you're unlucky). After that, it's primarily just getting the remaining bounties (min. 120 runs), leftover stuff from the House Contractor, and the Resources Director, which, unless you mod the game, will take a ridiculously long time to complete.

[admiral1018]

Yeah, first ending and the game credits come after your 10th escape. The second ending, referred to as the epilogue in the achievements, is about 40 or so runs after that.

Generally most people should be able to do all story-related activities and the prophecy lists within 100 runs. After that it's buying everything for the house, possibly maxing a final mirror item or two, maxing infernal arms, earning badges, and getting higher heat clears.