I've been using Events and Decisions for awhile now without any problems. I download this mod and now once I get into the medieval era, around turns 150-200, I'm no longer able to reload previous saves. The E&D menu stays locked in place and can't be moved. While I'm not 100% certain that it's the Enlightenment Era causing this problem, I don't know what else it could be. This is the most recent mod I've downloaded since these crashes started. I don't want to have to delete this mod as it seems fantastic, but I would also like to play a game into the Medieval era.
Here is my mod list, it's quite extensive.

.England - Toft Flags
Less Warmonger Hate [BNW]
Religion- Improved Customization
Civ 5 Improvement patch
Resource- Granary Includes Bison
Barbarians- Unlimited Exp
Naval Healing Mod
(BNW) General Heroics
Contextual Unit Names
Dynamic No Obselete Units
Leaders Like War
RED Xtreme
Pantheon
Three Gorges Dam
Mount Rushmore
Cologne Cathedral
Empire State Building
Panama Canal
Erie Canal
Lumber Mills on Jungles
BNW Alamo
BNW World Trade Center
American Wonders Pack
Promotions- Ancient Ruins Choice
Civ 5 Diplomacy values
Barbarian Immersion Enhancements
Pontoon Bridges
Artificial Unintelligence
Units At Half Cost
Buildings At Half Cost
Trading Posts Grow Into Towns
Really Advanced Setup
Half Inflation
Arecibo Observatory
Brooklyn Bridge
RED modpack
Titans of Commerce, Science, and Industry
3 Units Per tile
Separate Great People Counters
Conquest for unique building
Infoaddict
Conquest for Unique unit
Town Square
Civ Names by policies
Natural Wonder Overhaul
Slower Science, Longer Eras
Barbarian Spawn Increase
Resource- Mint Includes Copper
Faster Aircraft Animations
Units- no futuristic units
Emigration
Stronger Guided Missile
Submarine Ignores borders
Scout Ignores Borders
Reforestation
The Motherland Calls
Colored Religions
Fortress Borders