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Game balance is always, ALWAYS going to be a matter of perspective and personal preference. That's why game difficulty choice is (or at least was) a thing. And that's part of the reason why mods are so popular - because they help players to customize the difficulty to their playstyle and preference. Unless we're talking about quality of life mods, I'd say roughly half of RimWorld mods are things that Tynan would consider bad for game balance.
So... no. I do not agree that the insanely high chance of cancer is a way of balancing it, especially since a way of fixing cancer does not even exist aside from cutting off the limb or body part or resorting to a mod. (Heck, there are barely any mods that can fix cancer. I know because I've really, really looked for a solution.) But then, that's my opinion. And the way it currently works does not fit my playstyle or preference.