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The Binding of Isaac - Xbox 360

RB = Q ---------------- [Cards, pills]
RT = E ----------------- [KABUUM]
LT = SPACE ---------- [SPAAAAAAAAAAAAACE]
LS = WASD ----------- [Isaac's legs]
D-PAD = WASD ----- [Isaac's legs]
Y = ↑ ------------------- [UP]
X = ← ------------------ [LEFT]
B = → ------------------ [RIGHT]
A = ↓ ------------------- [DOWN]
RS = ARROWS ------ [ARROWS]
START = P ----------- [The "Just a moment" button]

You can skip Isaac's nightmares and the starting scene with LT
You can use the RS to navigate the main menu
You are free to change any key by clicking the Controller Companion's taskbar icon and going to profiles
Shooting (or crying) with the Right Stick WILL mess your hand

!! Thumbs UP !!