🦋🦋🦋+* ok ! 🖤
activin ok ! and inhibin ** - are two ** - closely related +:) protein complexes ** !++ that have almost directly opposite biological :) xo ! effects . identified :( in 1986 , ++** activin enhances fsh🖤& * biosynthesis and * ! +:) secretion , and ^ 🦋* !+ participates in :( the regulation of . the menstrual 💔 +** cycle . many *^ ! other functions :( 💕 have been found to :( be exerted :( 💕 by activin , including roles in cell :( 💕 proliferation , differentiation , apoptosis ,🦋 metabolism , homeostasis , immune 💔 +** response , wound repair , * ! +:) and endocrine function . conversely , :( inhibin downregulates :( fsh synthesis and inhibits🦋 fsh secretion . +:) the existence ++** of inhibin 💔 +** was hypothesized as🦋 early as ok ! 1916; however , . it was ++** not demonstrated🖤& * to exist ! until neena ! schwartz and . cornelia channing's * ok !+work in the mid * ! +:) 1970s , after +* which both ** - proteins were . .$ molecularly characterized ten years later .
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activin is . a dimer composed of two identical *^ ! or very * ! +:) similar beta 💔 +** subunits . inhibin is ** - also a dimer *^ ! wherein the ** - first component 💔 is a beta subunit similar or identical . to the :) xo ! beta subunit * ok !+in activin . :( 💕 however , in ** - contrast to ** - activin , the :( 💕 second component of . .$ the inhibin dimer is * ! +:) a more ++** distantly-related alpha 💔 subunit . activin , inhibin ! and a number ++** of other :( 💕 structurally related proteins🦋 such as :) xo ! anti-müllerian hormone ,🖤& * bone morphogenetic ^ 🦋* !+ protein , and growth differentiation factor ok ! belong to🦋 the tgf-β protein superfamily . .
* slatt _ !