A number of the medals can be glitchy including; Explorer and Deep Breath. Be careful not to die in the sections of these medals because it's reported you may need to restart the game if they mess up. Also keep a close eye on 'Geelk' for not failing any hacking attempt but you can abort these with 1 without it being considered a fail and retry.

Supersonic is not present on the PC medals list so any ammo type can be used through the game.

Challenge room with only water powers is very easy, just spam the tower around and press v every so often. Then clean up any survivors one by one.

Text collectibles guide (includes locations, hints of medals) - https://steamcommunity.com/sharedfiles/filedetails/?id=516129523

Youtube videos showing collectible locations (not all of them link up with the order in the text guide so check in video info for the needed collectibles) -https://www.youtube.com/@goTha83/search?query=hydrophobia

Baba Is You is a difficult and increasingly abstract puzzle game. For this reason even with guides it can be confusing and at times tedious to complete but it is certainly possible.
The first two links are for a steam guide and the hub worlds section of the games wiki, both of which have plenty of good solutions but both of which had issues with some solutions so it is recommended to switch between them if it seems a sites solution isn't working. The third link is to a Youtube playlist which contains video guides which were not fully checked but when tested worked well.

Steam guide -
https://steamcommunity.com/sharedfiles/filedetails/?id=1736747332

Hub World section of games wiki -
https://babaiswiki.fandom.com/wiki/Category:Hub_Worlds

Youtube Playlist -
https://youtube.com/playlist?list=PL4NE6RuZnnWMWBMEUTNFwiZoTVU_3jkPI&si=eacMkaNwyqsW0q0c

Neither of these resources are perfect on their own, but combined they should give you a clear idea of what needs to be done to get all the achievements. The Hell Loop DLC is not required.

Youtube video guide; Includes the strategies for obtaining some of the relics- https://www.youtube.com/watch?v=BURyWWXmG88

Steam guide; Tells you which levels you may need to go back to for some of the relics in Chapter 5. If you get stuck on Chapter 5 Level 4 you may need to alter Chapter 2 Level 1 slightly - https://steamcommunity.com/sharedfiles/filedetails/?id=2104737479

Achievement tips; https://steamcommunity.com/sharedfiles/filedetails/?id=1593971336

Filled in map with all items noted; https://steamcommunity.com/sharedfiles/filedetails/?id=642031075

Guides:
Guide for destroying all 4 rock portals before end of day 25;
https://steamcommunity.com/sharedfiles/filedetails/?id=2069289307

Once you survive the final counterattack this will pop if it is day 25 or before.

Guide for surviving 100 days:
https://steamcommunity.com/sharedfiles/filedetails/?id=2282992537

This unlocks morning of day 101.

You can definitely deviate from the timings mentioned to some degree but the guides give great strategies to use as a base of your plan.

Miscellaneous achievements:

Some information on the miscellaneous achievements although not complete. More details on the trickier ones are below.
https://steamcommunity.com/sharedfiles/filedetails/?id=540373679

On the Fourth Day We Had a Feast
Incorrect description. It is only 10 deer but the 10th deer MUST die on the fourth day. Run past deer to make them run towards camp then herd them into your archers.

By the Seventh Day I Cleared an Acre
Unclear but it seems that this is unlocked by clearing enough trees to remove a vagrant camp on each side of the main camp. Can bribe enemies with 1 gold each to allow builders to work through the night.

On the Eighth Day I Fumbled
Villagers can drop coins on the floor, it is the coins the monarch drops that cannot touch the ground. Line vagrants up with the monarchs legs on the horse before dropping coins and they should be caught by the vagrant in midair.

On the Ninth Day I First Ran
Need to wait until the 10th day sign has appeared and disappeared. After that run for the first time and it will pop.

The Tenth Day We Fought Back
Only need to destroy a single portal for this to unlock.

Tips and Strategy:
Progress is only saved when you click 'save and exit'. This can be used to set up checkpoints every few nights that can be reset to in case an attack is sent the wrong evening or enemies break down the walls. Definitely recommended to save often on the road to 100 nights.

Builder shrine adds an extra 80% of the walls hit points and the archer shrine increases damage of arrows. Both are highly recommended for the later waves and the counterattack waves that occur after a portal is destroyed.

Blood moon nights are followed by a night of no attack. Use this time to fill up the shrines and recruit as many people as possible.

Farming is not required, archers with bows will be able to hunt enough rabbits to fill your wallet well enough. Ensure not to knock own too many trees otherwise your archers can get too far from camp to get back before the attacks hit.

You need to find and upgrade the architecture shrine (wooden structure that almost looks like an altar) before you can reach fully upgrade the main camp. This is needed to be able to recruit knights who lead the attacks on the portals. Knights can also be fed 7 coins to increase their resilience. Make sure to time your own attacks so they aren't caught by enemy waves moving towards you.

Daredevill (Beat 100 challenges)
Open the 'Rampage Challenge' on the main menu, let yourself die to the first enemies, rinse and repeat.

Godlike (Beat campaign on hardest difficulty)
You can play the majority of the campaign on easy difficulty, then change the difficulty to veteran in the in-game menu for the final stage of the final boss. As you need to get to NG+3 for Frenzied you have time to figure out when that is.

Frenzied (Kill 100 enemies in a Frenzy)
Frenzy is the powerup that is shaped like a pills. These 100 kills need to be in a single instance of frenzy which is why it is likely impossible before NG3. To get it, ensure you fully upgrade the perk related to combo chances, buy a lot of explosive ammo and once Frenzy kicks in spam the explosive ammo. It will unlock at wave end if you obtained it.

- Stealth Master Video Guide, All levels - https://www.youtube.com/playlist?list=PLAtQpRVrE5Z7i-ohsf4O6iw9NE2nxbXow

- Miscellaneous Achievement Guide (read comments for 'Engineer') - https://steamcommunity.com/sharedfiles/filedetails/?id=1520379044

- Achievement guide https://steamcommunity.com/sharedfiles/filedetails/?id=2457573294

- Script for 100k 'No' idle (F2 for on/off)

F2::
If State=50
State=Off
else
State=50
SetTimer SendKey, %State%
Return

SendKey:
Send {space}
Return

Achievement guide - https://steamcommunity.com/sharedfiles/filedetails/?id=1162293689

Video guides showing challenge rooms - https://www.youtube.com/playlist?list=PLOoqAyisGj4e1t_hkOeZrYjBL-CAlOUmu
The challenge room at the beginning of ???? counts into the Volcano level.

Inkinator - Do this at the beginning of Volcano approach on the enemies you are supposed to dash through to get off the pirate ship.

Fanciest Fighter - If you need to grind squiggles after finishing everything else, it's fastest to grind them in the blocks after the Bathtub Tower.

- Achievement guide: https://steamcommunity.com/sharedfiles/filedetails/?id=1716674223

- Additional info for Psychotherapy: https://www.trueachievements.com/a311198/psychotherapy-achievement

- Speedrun Aid:

The overall medal is taken as a point average of your individual level medals (Platinum = 4, Gold = 3 etc) For that reasion aim to get as many platinums as you can in the earlier levels, this will greatly help you by covering if you dip into a silver/bronze in later levels.
Choose your sword wisely, Some suggest the master sword because of its projectile, however I found I kept focusing on trying to be fancy with that rather than focus on my character and as a result I died. In the end using the base katana is what did it for me, your mileage may vary.
https://www.trueachievements.com/a311198/psychotherapy-achievement