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Fire grenades = Gammas in their open mouth, Nemesis burn damage
Acid grenades = Betas (seems less effective than fire vs gamma but loading screen says this)
Explosive = zombies, stunlocks Nemesis
Mines = personally used them right after picking them up as they are suited to that part.
Hand grenades = zombies and Betas
Not tested the fire damage but in RE2 the fire burn damage wrecked bosses so likely the same with Nemesis.
The Betas have armour so the acid melts it off. An acid round/shotgun combination would probably work well. I was seeing the armour blast away when I was feeding them buckshot. And acid rounds have always been a weakness for Hunters in RE games.
Not when I shot them with it...... 2-3 shotgun blasts all it takes for those.
Edit: as for the op, tbh the only things the acid rounds felt useful for were those naked zombies and hunters. I never used them on anything else, threw a few at nemesis 3rd form but did not seem to do much.
{LINK REMOVED}https://www.gamersdecide.com/articles/re3-remake-best-grenade-rounds