Lore question(SPOILERS)

[sergantuss]

So i dont get it.
Is rats coming in cuz there is Prima Macula member or Prima Macula member start to *wake up* cuz there is a new plague(rats) coming in?

Cuz if the prima macula member is like a *choosen one* that need to stop plague then why mother is tryed to cure him(who will stop the plague then)?

There is info that prima macula member can die during his *power up* moments. Is it mean that if boy will die its mean that there will be no safe vs rats and world is done?

[KingPopinLockin]

I believe the reason the mother is treating Hugo is because the Prima Macula harms the carrier. They never say they are trying to "cure" Hugo, only "slow" the process. I think the mother is trying to slow down the first threshold, the point that Hugo can use the abilities, is because he is too young to wield such power and because the onset of the first threshold is painful and may also be physically harmful for a 5 year old to endure. As you said, they hint that the threshold can kill you.

I'm not sure if the prima macula carrier dying is the end. It seems like one person is chosen from a particular bloodline to hold this power. They also mention a part of lore that says something like "digging deep down will reveal the stone" probably the philosopher stone which is tied deeply to alchemy itself. These are mysteries that may only be answered in the sequel.

To give a more definitive answer though. I'd say that no, the death of the carrier doesn't necessarily mean game over for Earth. The main villain gains his powers by taking Hugo's blood which gives him equal powers. It would be possible to take Hugo's blood and make virtually anyone a carrier as long as they survive the process of hitting the threshold. Maybe if the carrier were to die without this happening it would mean the end but as long as the power can be given, or even taken for that matter, there is a way to still stop the end.