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Not at all. The goal is to have it at 100%
The higher the percentage of the genome you have the more you can do with it and the better the odds of a successful incubation.
If you have a dino at 100% Genome it has 100% viability
Making modifications lowers viability. So it's a lot better to start from 100%.
The base viability (chance of incubating safely) of your dinosaur is also equal to the genome percentage you have. Which means the more percentage you have, the higher the chance of incubating safely.
Finally, as you increase the genome percentage, you unlock more gene modification slots, the last slot for each dinosaur unlocking at 100%.
To summarize, high percentages get you better dinosaurs, safer to incubate, but also dinosaurs you can modify more (because more slots, but also because the increased viability gives you a better ability to modify the genome, as gene modes decrease viability). A 100% genome dinosaur is one that you can get to its full potential as an attraction.