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I don't think you even can get a blood shrine to kill you. If you spam it it won't do it.
So if you have 500 hp
The shrine deals 250 damage
You gain ~125 gold
You get half of the HP you lost as Gold.
So at 100% health, you lose 50/75/93% of your health and get 25/37.5/46.5% of your health back in Gold.
Just as a funny side note, Tougher Times can block the health loss of Blood Shrines.
I know it does scale based on maximum health, but not so sure about the calculation. Have to check it to be sure.
Also, barrier effects like the one from aegis absorbs the damage from the shrine, doesn't add value however.