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turn your brain off and spam charge shots
VIM is also good but I prefer the sludge blast
I usually just throw in the wave cooker with cotangion transmitter to stack extra debuffs
Subata for convenience against other targets; tranq rounds OC will slow dreads even if they're immune to stun
EPC TCF for pretty much everything as usual, but especially Hiveguard's armor phase and the Persistent Plasma OC is a pretty nice "get these swarmers/naedocytes off me" button when exploring. You can't go wrong with Burning Nightmare + Heavy Hitter OC for simplicity if you don't like TCF; having access to fat damage and fire makes most obstacles easy to handle.
Wavecooker neurotoxin is a no brainer, but you can also spec it for Boiler Ray and gesture in the vague direction of swarmers (particularly the normal dread's swarmer ball attack) to explode them all. Radiation OC is convenient for the double-feature of the radiation proc and also narrower shots make it much easier to avoid friendly fire.
Dmg build - 13212, volatile impact oc
To help with regular enemies - subata
To use during dreadnought fight - colette with blistering necrosis oc
sludge blast is best for this due to its high spike damage but you might also prefer a VIM build specced for normal shots
Also I take double damage mod C4. Sludge is very awkward vs Hive Guard's armour phase, but one good C4 can almost kill all three weak points on haz5.
Goo Bomber Special, then EPC with Burning nightmare to shoot through the dread and set the goop on fire at the same time.
Add neurotoxin grenade for another DoT and dreads are slowed to no end.
Make sure you set it on fire after you let the neurotoxin tick a bit, so you dont instantly explode it.
Its less effective on the twins, but all sludgepump builds are. Its still pretty good and fun to use.
volatile impact mixture or sludgeblast if not
Hydrogen Ion Additive (normal shot)
Sludge Blast (charge shot)
Disperser Compound (charge shot)
Are all pretty good for elims. You can use other OCs as long as you build appropriately.
Do note that you'll be using normal shots more often for utility when using charge shots. Charge shot builds want charge speed in order to take advantage of vulnerability windows.
For all builds in T5 either is good: You can go slow for better kiting and/or team utility. Or you go DOT damage if you're confident in your kiting and don't feel like you need extra slow.