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I've did that for a lot of my leveling using armor with the "Suppression and Health Regen % equal to missing health" Relic buff and it worked really well.
The best build I ever ran with that armor had the Artificial Organs II perk which essentially meant my character was stuck at 50% health all the time, and then used a lot of +Dam%=%missing health .... it's rather effective.
Out of curiosity, if you are going the Augmented Boby route, why not just upgrade to Augmented Body 2 at end game so that Suppression is always 100%?
I've been tempted to try an Augmented Body II build but I just can't give up my practical immunity from stacking regen and Artificial Organs II plus damage mitigation from Crisis Management. I lose health quick down to 50% health and then nothing can kill me.
heh, apparently. Have you ever played around with the Artificial Organs II + Crisis Management pairing? If not, give it a try some time. Talk about tanky!