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There are two endings in the game. Okay, three, but the third one feels more like a non-standard game over. Which ending you get is determinde by a single quest on day 11: if you do trace the papers and bring them to General Block - you get the Day ending. If you burn the papers - you get the Night ending. That's it, no other things you did or didn't do not affect the ending. You can try and find the panacea, you can abandon it entirely. You can run around town like madman trying to help everyone or you can kiss the town goodbye and concentrate on your own survival - nothing changes in the global picture of events.
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Now, the Day ending allows you to free roam around The Town and talk to everyone of importance. Those who died are replaced by shadows (or tragedians if you prefer), so you can't really have any dialogues out of them and learn of what they are going to do next. So, this day 12 is the closes thing you get to those classic Fallout-style "where they are now" endings.
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As for reasons for saving people... Well, because you like them? Or because you feel like you have to? Why did you play the game at all? Technically, you don't get anything out of it, the game doesn't really punish you for not saving someone. Aside from cutting you of the piece of content. Which, actually, corresponds with the main theme of the game: your life is in your hands and you can do absolutely anything you want. At the same time - you're never alone, and things you do will affect others, so be prepared for concequences.
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The fate of The Town after the outbreak (in case of Day ending) is very open. And that, again, I think is deliberate. Pathologic tells the story of overcoming the crisis. Techincally, whatever happens after is not relevant. At the same time, it's one of the themes (again): yes, you do whatever it takes to live another day, but if you stop and think for a moment, you'll see how that "whatever" can shape the history long after all the dangers are gone.
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In the end of the day - does death of bound characters affect the ending? Yes and no. From the gameplay perspective - no. From the story perspective - no, because the outbreak will end one way or another. And yes - because everything that happened in this story will shape the future story of the Town.