Proof that Misao and Mad Father are connected. (Spoilers)

[R1ch4rd N1x0n]

Misao has a "doctor" enemy that heavily resembles Alfred Drevis, which some might have just thought was a coincidence, but I've found enough evidence that confirms that he is Alfred Drevis;

1. They look very similar and both wield chainsaws. Their resemblance is most noticeable when comparing the Misao doctor to Alfred in his last appearance during the true ending in the lab, after collecting all 20 gems.
2. The lab looks very similar to the lab found in Misao.
3. The Misao doctor's filename is "zombie_madfather."

Also, there is also quite a bit of evidence that shows that "Miss Library" is the clone of Aya, created by Alfred, which is seen in his last appearance in the true ending after collecting all gems;

1. Many of you may not have noticed that "Miss Library" in Misao greatly resembles Aya, most likely due to her glasses. However, it is possible to see her eyes if you see her while she is "surprised" and her eyes look exactly the same as Aya's.
2. Attempting to name Miss Library "Maria" prompts her to respond saying she doesn't like that name.
3. Attempting to name Miss Library "Aya" prompts her to respond "only my father can call me that."
4. Talking to her can have her mention having a father who locks himself up in the lab all day doing experiments, just like what Alfred does in the Drevis Mansion's basement.
5. A picture of Monika, Aya's mother, can be seen in Library's bedroom.

Additionally, Ogre and Onigawara are heavily implied to be the same person. They look and behave very similarly, and upon seeing the Aya clone, he "welcomes it into his world" which almost certainly means the "other world" that the school in Misao was sucked into.

All this evidence above has brought me to this conclusion - Misao takes place after Mad Father. Onigawara is Ogre, the doctor is Alfred Drevis, and Miss Library is the Aya clone.