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Dump the germy slime in water and forget about it. Germs are not deadly, actually pretty harmless and your dupes will recover usually really fast.
Just seal up the polluted water pool, clean the oxygen (if you want) and keep on digging.
Of course there's always the option of digging around the slime tiles.
However now I'm using the increased diseases, it really changes your game. You actually need to use medical stuff. You all should try it.
For example now slimelung generates two more diseases and is fairly lethal and needs to be avoidided or dealt with. Have a few key dupes die and you'll want to deal with slimelung. You really need to understand slimelung to deal with it.
It spreads very well through po2, but doesn't spread and slowly dies in o2 co2 etc. Deodorizers slow it but do not stop it. It will creep into your base so you have to be proactive. You'd like to avoid contaiminating new sources of ph20, at all cost. Cleanup is to pump slimeair into tanks in chlorine. Along the way of clearing slime, you will need as mentioned probiotics (helpful germs). Planting buddy buds is very helpful. That plant has gone from stupid and a waste of resources to perhaps as valuable as the most important things, imo. I consider worts ferns and buddy to be the most valuable things, I guess that's because they cannot be produced. What do other people consider most valuable?
For low germ count you can use depleted uranium metal tiles. I have some in my water and it's enough to keep it sterile. If new germy water comes in and runs over the metal tiles, it takes a few seconds to get disinfected. For slimelung pouring some radioactive waste could help if the area is not too big.
I don't really deem any of the limited resource things too valuable (except wolframite, which is not always limited). Buddy buds are nice to the stress relieve, but ~2 of them are usually enough and technically bristle blossoms can fill in a bit. The next patch will likely also add a critter that disinfects water. They just changed it again, so it's not super clear how that will turn out.
How do I get higher stress? Because I'd like to have to deal with that more.
When I was playing vanilla base, stress can be ignored, some good food seems to pop them over.
I turned on the DecorReimagined and now I'm having stress difficulties but wouldn't mind more so there's actually a reason to build some decor. I've never had to build decor, or bedroom, or shower or anything to relive stress, the morale is always so high.
I also had natural gas so I had surfnturf and maybe that helped. This run seems to be very difficult - no gas, no metal volcano yet. Just slush and hot polluted o2 and cool steam, seems challenging to me, I'm trying to find more vents but slimelung epidemic is slowing me down.
Decor, bedroom and most other things mostly just stack morale, but you can't get more than -20% stress from morale. Apart from the soul food buff, food also just stacks up morale.