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For a great airlock, you can create a U shape of 3 square tall, and fill with water, so your dupes can travel across.
Keep then to eat raw meals, and recicle urine. In time build a farm to cool off your base.
i kid i kid. its something i wannt try though at some point. just heat it up to the point all the slime cooks and the waters boil, then extract all the heat into a steam turbine.
i usually build a ladder grid and dig everything out top to bottom, build a storage room to store all those materials specifically incase they got germs on em and fill with chlorine. as for the slime i put that in a water storage bin to use for farming. i find digging it out by hand is often the easiest method. then if there is a natgas vent in that particular biome, i turn the entire space into nat gas storage and distribution. works pretty well and has a decent capacity usually. the vent will go dormant and if its sizeable enough i never run out of fuel.
My latest map, I actually got to try the 'burning it off', My Volcanea (SUPER Ironically spawned with 0 volcanoes) Came with the modifer: magma channels.... however not everything was abyssalite proof, and about 5 biomes had Heat pouring in.
So i insulated the biome off and eventually tackled it with atmo suits.
At which point, the coolest part of those slime biomes was roughly 150c+, and up to 400c+, so no more slime lung :D
As for general strat: I agree with Xilo for a general strat.. Also digging from the bottom up works as well, so long as slime falls into fluid, it wont offgas, releasing the slimelung.
storage containers in water with VERY HIGH priority, (or even better: teh only containers to exist), means that slime will quickly be taken to a submerged container where it wont offgas.
Slimelung is harmless if its in the water or on solids. Its only an issue if its breathed in. *(in any of the many ways it can get into the lungs of duplicants)
As a new player: go slow and steady, and deodirize EVERYTHING in case something goes awry, and make sure contaminated blocks mined fall into liquid, or stored in a container that is in liquid.
A little bit of healthy respect for the pathogen goes a long way to making sure your duplicants stay happy and healthy ;)
it's not like slimelung can kill dupes anymore so it's really only a matter of efficiency at this point and taking elaborate measures is highly inefficient.
i build a few storage compactors in a small pool of liquid and set them to store only slime, priority 9
Next, i send dupes in to build autominer/battery/manual generator "units" and let them dig it all out... the dupes grab the slime and dump it into the storage compactors for later processing.
build a bunch of deodorizers and let them clean the air for a few cycles.
Some say strip out the whole biome, some say pump magma in and burn it all. Personally, I keep it mostly intact and sterilize the open spaces once construction is done. With some pips, reed seeds, arbor seeds, shine bugs, and plastic rooms, it looks nice. Glass in your pacu ponds too. Just because you can, not because it is or is not meta.
besides exo suits allow them to go into the heat and cold and not complain about it. more or less its a morale boost of sorts.
As long as you have good O2 saturation slimelung is not a big deal. If you have a low O2 problem you can run into a loop where people are trying to decide if they are going to eat or breathe which can be frustrating but honestly if you are hitting that you have bigger problems than slimelung.