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I dont know. I barely killed him on classic.
I started the fight in the foyer also, so I wasnt surrounded right away.
Anyway your best bet is to have the ranger and rogue correctly built and try to take down his armor using the green tea buff and chameleon cloak to not take damage for 1 or more turns.Then just use knock down arrows and other knock downs you have.If that's not enough either just craft a lot of skin graft scrolls so you can keep on resetting your abilities.
There's probably more advice other people can give you but this is all I could think of right now.
If you do her quest she debuffs the doctor at the start of the fight,can't remember what the debuff is exactly but I think it reduces his armor values by a decent amount.
Spoiler: Lohse can reduce the Doctors armor/health via her personal quest plus her being present during the fight causes the Doctor to channel during the first 3 turns instead of attacking.(after that he permanently mind controls Lohse).
Impossible until someone comes along and shows how they did the whole thing on tactician using only one character, which will happen.
Adra has less armor/hp but remains strong. the others advantages of making the quest for lohse is to have a very good wand for geo and during the fight, the nemesis don't appear. so you don't need to kill these 4 powerful enemies.
moreover when adra starts the fight (demon initiative) it's better to be on the same level as him otherwise you die even if you weakened him or you need to have companions with a very good level of magic armor and/or good fire resistance to resist.
you can also attack it before the start of the fight and therefore before it turns into a monster (you "break" demon initiative)
In this case you can protect your initiator and possibly other team members.
If you do the lohse quest, if I remember correctly, adra doesn't try to take control of lohse and you must fight him. (or then you can accept the pact when you have lohse as a leader)
yes killed adra +7 level mod solo no lone wolf. (can do more) without the demon's initiative. (adra = 97k magic armor + 46k HP)
I personally lured all the nurses outside and killed them before attacking the doctor. Also, not sure if this is a glitch, but you might be able to prevent him from transforming by casting permafrost on him while he’s talking to you (I forget the spell name, maybe cryo stasis). It’s a hydro spell that freezes you for one turn and heals you on the next.
He’ll skip his first turn, where he would usually transform, and then the fight is cheese from there.