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2) If you don't want to do the first one, drink fire resistance potions (his Supernova deals high amount of dmg, it can one shot you)
3) Depending on where you came from (cellar or front doors), try to lure him into a smaller room (so you don't get attacked from many sides).
4) Don't have your characters too close to each other (Supernova is AOE spell).
Because he dosnt do anything when Lohse is immune to Charm:)
Other than trying to charm her:)
Secondly, you can use his minions against him. Craft a mind maggot grenade and try to strip magic armor off his minions. I've done this such that I charmed about 7 of the demons and nurses, letting them soak his attacks for me as well as dishing out damage for me.
Lastly, go collect a bunch of chairs, paintings, barrels and crates. You can pile them up as walls before initiating the fight (or do it by sneaking in if they're hostile) and block his nurses and demons from being able to move towards you. This can buy you valuable one on one time with him, giving you the breathing space to try and take him out without worrying about his minions.
Can that appear as an affix on random items, or is it a unique one-off thing?
(Level 20, classic difficulty, saved the souls, got 2 achievements.)
Thanks mate!!
I divided the party and started the conversation with Loshe, then took the rest of my gang and killed all of the nurses not in the conversation.
Just killing the nurses wasn't enough to give me the edge I needed though, so I then TP'ed all of the nurse corpses (5) right next to the Dr, and just before kicking off the fight made sure that my mage would win initiative.
The fight started with a Mass corpse explosion that knocked out 2 of the Drs minions, torched his armor and kicked the demon down to 1/2 life. Demon was dead before the end of round one and the rest was just cleanup.
Super-cheese but ohhh the explosion was glorious.
"Hey... what's your friend doing with that corpse??"
"Oh, nothing... let's keep talking about my soul".
My suggestion is looking up min/max builds. Other than that, you're going to need pure skills even when using the shadowblade stealth cheese tactic or the lohse anti-charm tactic. You're not going to defeat her on the first playthrough if you're new.