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Avoid her attacks because her poison drains stamina and that will kill you fast. Ignore the skals, use ranged attacks on Doris. Hitting her with melee/touching her in any way might poison you. Bring your best guns but don't use them unless you think you can kill her on that attempt (ammo and serums don't come back on death). Take your time, Ultimate her to death if you don't have anything else. Save the blood for healing unless you've got a full tank. I like Blood Cauldron for this one because of the AOE. Abyss is also good. You can hit her while she's Abyssed.
You can run out of the theatre to upgrade and respec if you need to.
I didn't focus on her adds because she'll just send more as you take them out, which can become quite frustrating and an unnecessary endurance fight. The idea is to take blood and use it, quickly and do as much damage as you can. I equipped an off-hand weapon that leeches blood.
Equally as important, dump a lot of XP into stamina. You will need to dash quite a bit to avoid her swooping attacks. And in this fight, you will probably experience your stamina being drained.
Tip: Use the size of the room to your advantage to avoid her adds and focus on her.
Source: Pacifist playthrough, and I was 12 levels below her. If I can do it, you can. :)
your char how ever takes full OR boosted dmg from all sources despite the game telling you other wise.
and disease type atk doing much dmg to the dead is just a joke lol.
Any time you see her begin an attack animation you spam space away. You get used to how she does her sword animations and you'll begin to find openings to get some hits in. Keep trying to bite her. To get some good damage off easily switch to your guns and use up ammo. You find a really strong gun before you fight her. Use it.
As for her minions, they're 1 hit kills. Just never slash them when their arms are up covering their face. I sometimes let them all accumulate and then use my ultimate which is the one that hits every enemy. That cleans them up. They don't really do much to you if you're focusing on dodging.
I beat her on normal difficulty and barely killed any civilians. I believe I was around level 23. Fighting her is what got me used to dodge spamming and with that I proceeded to beat rest of the game bosses really easily despite them being harder than her.
You seem to post this gripe in various threads- if the game isnt for you, so be it- not every game is going to please every person. But that doesn't means others, even many others, will agree with you; many clearly love it, warts and all.
FWIW, to the lurkers, curious possible buyers etc etc.... Jonathan is a 'new born' vampire... why should he have special resistances/defences/etc- he has to learn what they are, and how to use them. (oh wait , he sort of DOES.... in the tutorial/intro chapter you automatically get Autophage lvl 1 (self healing) and then one of the basic skills (claws etc) of your choice. Plus he can't actually die.... if his stats fall too low (which would kill a mortal and thus end the game) he just respawns someplace nearby, low on blood, which can be replenished easily with rats (or embracing (drinking the blood of, and thus killing) NPCs) And other RPGs have players start with nothing whatsoever making Jonathans minimal starting kills seem like a treasure trove (Long Dark comes to mind- all skills start at 0 and all require quite a bit of work to level any of them up to a point where they make any difference to your character's ability in those areas (firemaking, hunting w/bow and arrow, hunting w gun, sewing/clothing repair, etc))
Part of the unique levelling up style in the game is due to the choices/consequences issues- are you a 'good doctor'? A blood sucking monster? Something inbetween (eg: perhaps a vigilante who only embraces 'bad' NPCs, such as those that prey on the weak, abuse children, or are murderers)....This is part of the game- what kind of individual / vampire are you? And what kind you are is going to affect which abilities/defences/etc you choose.
lol.
LOL.
Good to know! i only did an over-powered -eat everyone- vampryr run my first play thru, and now, on my 2nd I am doing a pacificist one. I am just a little bit before this scene, so that reminder should be a helpful one to keep in mind, thnx!