what should i do after finishing the main story?

[treacherous]

im at level 48 playing moze i have all the dlcs but i dont know what should i do and which mayhem level should i play on??

[Ailes]

I would suggest playing the DLC in release order, as there are (if I remember right) a few references here and there about characters you meet in previous DLCs. I remember Moze making a few voice statements about a person, even if they may be easy to miss if you aren't paying full attention.

Maybe also activate Mayhem mode (and if just a lower level of it) so that everything scales with you properly. Otherwise stuff may bore the hell out of you. I don't think guns get blatantly stronger per-se in terms of direct stats with higher Mayhem levels (everyone else please correct me on that if wrong), but the chances of them spawning with good anointments/buffs that can significantly improve the performance of gear and of your skills (there are anoinments that heavily buff Iron Bear directly) is much higher. But it can be very hard to chew through enemies at too high Mayhem levels at first, at least without Iron Bear. You can test it out yourself, switching Mayhem levels generally is very easy to do on the fly, especially if you're in Sanctuary. I enjoyed experimenting with it more often than not.

Be aware that vehicle combat can be needlessly difficult when having higher levels of Mayhem mode enabled. Whenever I had quests that involved vehicle usage I disabled Mayhem. I also disabled it when I did some Vault Card challenges that involved a large number of kills of XYZ. My impression was that these challenges (or more precisely their XP rewards) do not benefit too much from Mayhem, if at all. And when it comes down to it you can (I guess) always do like 99% of the kills without Mayhem and then the last few ones needed to finish the challenge with it.

[Kobeth]

Before activating Mayhem, do the first mission of Ava's mystery podcasts side quests, at the end of the map there is an enemy called Sumo, farm him until he drops a Re-volter shield and equip it. After that, return to sanctuary, go straight to Mayhem 11 and go tip Moxxi until she gives you a Crit. You are now ready to start your journey into Mayhem 11. First thing I would suggest doing is playing the Handsome Jackpot DLC until you reach the Scraptrap Nest, you can farm the Nest until you reach max level. Moze probably has the easiest time transitioning to M11 because her mech has crazy Mayhem scalling, but this strategy will work with any character.