Worst first villain turns.

[Canard_de_Bain]

Dreamer with 2 dark heroes, 2 tooth fairies, 2 apes, and 2 others. Like, owww. Unless I drew into Rampage, I would not have much chance. Oww

[Mr Mopsy]

If you really want to make it hopeless Kvothe Argent Adept as the 5th hero would have 1 hp remaining after that first turn barrage.

[MechaMarshmallow]

I don't remember the exact combo involved, but a while back Baron Blade comboed enough cards on his first turn to end the game on me before I got to do anything.

[Deej-O-Matic]

引用自 MechaMarshmallow：

I don't remember the exact combo involved, but a while back Baron Blade comboed enough cards on his first turn to end the game on me before I got to do anything.

That would be impossible, since his game over trigger is a Start of Turn effect. However if you destroy the Mobile Defense Platform and even one more card hits his discard pile (possible through a lot of ways) before his next turn, then yes, you'd be hit with a Second Round Game Over if he got the perfect opening play of all 4 Hasten Dooms into Consider the Price of Victory and are playing on Advanced with 5 heroes.

[Deej-O-Matic]

引用自 ordalca：

引用自 DOLT Paladin：

I think Iron Legacy has one possible opening that will wipe any team. I forget though, I don't play against him much.

H=5
Setup: IL plays 2x Galvanized, 2x Demoralizing Presence, Final Evolution.
IL Turn: IL plays 2x Former Allies, Rule from the Front.

This first turn deals each non-villain target 5 toxic damage, then 8 melee damage, then all hero targets 7 melee damage, removes their hands, and then deals another 2 psychic damage, for 22 damage each (before nemesis boosts, which give another +3) before the heroes get to take their first turns. The heroes will have no hands and any power use will heal IL for 2.

The heroes then get their first turns, with only the Sentinels, F6 Tempest, F6 Unity, and POF Wraith able to have been incapped, with all but the Sentinels falling exactly due to Nemesis damage. As this setup requires 5 heroes, at least one hero remains standing.

Dropping the hero count removes at least one of the boosts or damage sources, so only the Sentinels would fall in that case.

Not quite a first turn wipe, but about as hopeless a game as you can get without actually losing straight out.

He's not in the video game yet, but Termi-Nation Absolute Zero would also be incapped by this setup, giving you your first turn team wipe.

I'm gonna dig around to see if there's any other "worst case scenario" first turns that could happen.

[Deej-O-Matic]

Here's one for a "worst possible second turn" for Deadline. It doesn't actively involve specifically shooting yourself in the foot, but it could involve not paying attention to what he may have played and some poor judgement calls of "you know what? we can risk him playing more cards."

Game: Deadline in Rook City with 5 heroes

Deadline's first turn
Deadline plays Pandemonium Key
EoT Deadline plays Unnatural Disaster
-Plays at least 2 copies of Calculated Orogenesis
-Plays any other 2 Catastrophe cards (at 4)

Player Turns:
A player reveals and plays Dr. Tremata
-Deadline plays Unnatural Disaster
--Plays 2 more Calculated Orogenesis
--Plays any 2 Catastrophe cards (at 8)

Another player reveals and plays Tony Taurus
-Deadline plays Unnatural Disaster
--Plays 4 Catastrophe cards (at 12)

Environment turn
-Plays Twisting Back Alleys
--Players agree to play the top cards of the villain and environment deck
-Deadline plays a Catastrophe card (at 13)
-Environment plays Twisting Back Alleys
--Players agree again to play the top cards of the villain and environment deck
-Deadline plays another Catastrophe card (at 14)
-Environment plays Ambitious Racketeer
--Pandemonium Key plays another Catastrophe card (at 15)

Deadline's Second Turn
-2 of the Calculated Orogenesis plays Blighted Streets
-Deadline plays a Catastrophe card (at 16)
-Deadline flips and destroys both Blighted Streets
-Blighted Streets play 2 more Catastrophe cards (at 18)
-Deadline destroys all 18 Catastrophe cards and blows up Rook City. Game Over.

The order of his plays can be done in any order, as long as 2 Calculated Orogenesis plays before his second turn and he gets Pandemonium Key in his first turn.