Wondering is there is Point and Click games like Anna's quest?

[RK]

Looking for a game where the story/characters are unique like this one
so far I've played Monkey Island series, Sam and Max, Grim Fandango , Deponia, Book of Unwritten Tales and now I'm on a search for a game to play

[MASTAN]

Deponia series and other Daedalic games.
Wadjet Eye games if you're not afraid of low-res graphics.

[Faedrill]

Little Missfortune, Fran Bow, The Dark Eye: Chains of Satinav, Memoria, The Night of the Rabbit, Randals Monday, The Whispered World, Silence, Toonstruck

[MASTAN]

Now I have more time, here's more specific information.
Here are only the games I've played, there are actually more.

Daedalic:
- Deponia series(Deponia: The Complete Journey / Deponia Doomsday)
- Edna & Harvey series(The Breakout / Harvey's New Eyes)
- A New Beginning
- The Whispered World / Silence
- The Dark Eye: Chains of Satinav / Memoria
- The Night of the Rabbit
- 1954 Alcatraz

Wadjet Eye: (pixel art)
- Blackwell series (Legacy / Unbound / Convergence / Deception / Epiphany)
- Gemini Rue
- The Shivah: Kosher Edition
- Shardlight
- Unavowed (same world as Blackwell series, little later in time)

Published by Wadjet Eye (also pixel art):
- Primordia
- Resonance
- Technobabylon

Pendulo Studios:
- Runaway series(4 games, may have problems with modern OSes)
- The Next Big Thing
- Yesterday / Yesterday Origins

Remastered classics:
- Gabriel Knight: Sins of the Fathers - 20th Anniversary Edition
- Day of the Tentacle Remastered
- Full Throttle Remastered

Other:
- Agatha Christie: The ABC Murders
- Alpha Polaris: A Horror Adventure Game
- Black Mirror series (1/2/3 - not the 2017 game, older ones, haven't played 2017's version)
- Black Sails - The Ghost Ship
- Broken Sword series
- Ceville
- Cognition: An Erica Reed Thriller
- Dead Synchronicity: Tomorrow Comes Today
- Gray Matter
- Hector: Badge of Carnage!
- Kaptain Brawe: A Brawe New World
- Kathy Rain
- Kelvin and the Infamous Machine
- Lamplight City
- The Longest Journey
- Machinarium
- Metal Dead
- The Raven Remastered
- Shadows on the Vatican series
- The Silent Age
- Still Life series(Post Mortem / Still Life / Still Life 2)
- The Tiny Bang Story
- Thimbleweed Park
- Tormentum: Dark Sorrow / Tormentum II

[Coach Gamer]

I would like to suggest The Last Door: chapters 1 and 2, released by The Game Kitchen, that released Blasphemous a few weeks ago.

Also:
- 5 days a stranger
- 7 days a skeptic
- 6 days a sacrifice
- Trilby's notes
They are DRM-free, you can download them here:
http://www.fullyramblomatic.com/5days/

Milkmaid of the Milky Way
https://store.steampowered.com/app/544970/Milkmaid_of_the_Milky_Way/

[Thesaya]

The Longest Journey, TLJ Dreamfall and Dreamfall Chapters. Simon the Sorcerer, Grim Fandango