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There's a chemical you concoct, maybe that's required to weaken him and that's when the cutscene triggers.
This is a remake, the guides you are looking at could be for the original PS1 game and things could be different.
Where you are standing could be the difference.
You may need to decrease its health to some degree.
Also chris can't concoct the chemicals
Take that!
Edit: To further clarify, "This only happens if..." refers to Rebecca busting into the room. If you got Richard the serum, the plant lets Chris go and you fight it alone.
Which might sound confusing to you but it's honestly the better outcome. It's an easy fight and mixing V-Jolt as Rebecca and running all the way back to the underground base to use it takes much longer.
https://github.com/Codeusa/Borderless-Gaming/releases