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If you have somebody psychically hypersensitive during an extreme drone you can give them anesthetic to knock them out for the duration, or put them in one of the free crytosleep caskets on nearly every map.
yayo is basically a hard pass in any situation. just sell it for cash and avoid all the nasty issues it will inevitably cause
sometimes my people got "accidentially" addicted from smokeleafs and there totally useless for days, wekks, even months... often go berserk, destroying legendary art or trying to kill other people.
i can't even imagine having one on yayo trurkey
AVOID THIS.
use teetotaler (or whatever it's called) to produce the stuff and sell, do NOT let them take it.
If I do use drugs to keep some problematic colonist (e.g. tons of psychic sensitivity) happy during a psychic drone, I just use smokeleave. It makes them rather useless during the duration (so better to avoid that too) and the buff isn't as big, but getting addicted to it is much harder. Just forcing recreation time in a beautiful room can work too.
Remember for the future that just because someone is barely out of minor break risk at some point doesn't mean that you are out of the danger zone. Misery loves company.