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It would be weird making everyone identical, as that would be cloning everyone but you could do that with the fertility and or growth vats, haven't experimented too much with it but if you take the same Colonist's extracted genetic info over and over and put it into a growth vat, it should make identical people each time, or at least people with very little variations?
All you have to do, is take 2 people as the source, male and female, and extract her ovum. Once every 10 days. You COULD then store them in a freezer location, and afterwards, when you have the amount you need, use the designated male to well, do work and make it into a fertilized ovum, and that grows into an embryo, and eventually, a fetus, then a child.
Effectively, ALL the children created this way are brothers or sisters, the only difference being their gender and if the parents have multi-gene selections, they may have different hair and such things. But only if both or one of the parents has such a gene array.
Voila, you succesfully engaged in a form of eugenics to create the identical, perfect or unperfect or just average human, and cloned someone, effectively.
The only issue is that the clones will only be the new generation, and not the current. I've loved to have seen a gene cutter or something where you could cut out genes you don't want, but you can't. You can though simply counteract genes that give a penalty with another gene that weighs up the penalty, clumsy movement weighed up with fast moving is one example.
You can, it just requires overriding all germline genes. Any gene in a xenogerm that does something similar to a germline gene will cancel out the germline gene. So you can replace trotter hands with elongated fingers or human hands, replace pig ears with human ears, replace pig nose with human nose, replace fat/hulk body with normal/thin body, etc.
If you want to make a pigskin into a pure baseliner, that's not really possible without mods. I think the Alpha Genes mod adds some tools that allow you to strip germline genes and such and allow you to turn anyone into a baseliner.
If you want to make a super xenogerm that replaces pretty much all functioning gene categories to create one unified species you morph everyone into, that is something you can absolutely do with xenogerms, and you can even make them look like ordinary humans again, but they are just going to have a lot more genes to manage. Many of the default "human genes" you have to buy or find through other means though, you can't rip "human nose" from a baseliner for whatever reason, but you can find the human nose gene out there.