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Instead you can instal pew legs (don't remeber how it's called for arms). But this is in vanila, in mods things may be different.
And when doing such sadistic thing - is completely up to you :)
Doing operations on prisoners is actually a good way to get medicine skill up on any doctors you want.
I do it when a raid actually does something damaging and puts me in a bad mood. I once had several failed installations of the peg leg that destroyed a kidney and lung. I was still able to install 2 peg legs and remove a jaw, plus those 2 injuries, release the prisoner for the 15 faction boost, and no joy penalty on the colony.
Late game researches allow for bionic arms. Peg legs are there by default, but other and more advanced prosthetics are unlocked via research.
http://steamcommunity.com/sharedfiles/filedetails/?id=725956940&searchtext=epoe
As to "when" should you do that - yeah, that's entirely up to you. If they will die without it, and you do want to keep them alive (say, they've got some uncurable disease that has something to do with that limb) - you might want to do that; likewise, use them to fix your own colonists in the time of need. You can also follow our resident Dr. Mengele Numbers's advice - by constantly operating on a prisoner, you can seriously train your surgeons (unless you want to use another mod for being able to train surgeries the way they sometimes do in real life on corpses).
http://steamcommunity.com/sharedfiles/filedetails/?id=672718060&searchtext=corpse
If you really want to train somebody, just get multiple people captured (the lower the starting medical skill, the more hostages you'd need; also, it's better to use raiders, so that losing reputation with them won't be an issue); make a prison infirmary (in case you didn't know, you can assign a bed to be both cell AND a med room), hook a vitals monitor to it (and you would REALLY need that thing if you don't want to run out of prisoners), and then transfer a prisoner there. Draft both your surgeon and some tough guy with a rifle, and order the latter to shoot your prisoner once. Ideally, you would also want some other guy with a good club - in case the prisoner wouldn't like your idea of fun and would retaliate, as you're more likely to just incapacitate him with a baton/club than with a few bullets in his face. Then undraft your surgeon and have him "examine" and "treat" the prisoner. If he's still breathing after that, do the whole thing again.
Once his health is dangerously low, let your surgeon and guards have a nice meal with a cup of coffee on a fine terrace overlooking the nearby lake, and let the inmate heal. Rinse, repeat. If your surgeon is already good enough, he/she would be able to keep your prisoner alive for indefinite amount of time. If he or she is not, well... You can use that as a sort of a very cruel execution method, too.
Just make sure your colonist armed according - assault rifles, machine pistols, turrets and some weakly-but-rapid fire guns. Charge rifles, sniper and shotguns are tending to kill and don't leave a lot of prisoners.
After installing peg legs you can then remove them, same can be done with wooden hands if you want to remove their hands.
Note that for arms you need something like Prosthetic arms that can be added then removed.
OP: As to "when to do it":
+ If you have a prisoner that tends to be a issue (prison breaks + good at combat and the like) that you still want to keep around (perhaps you are extracting genes, or using it as a blood farm or whatever).
- However note that this comes with a time cost for your pawns, without mods someone needs to take time out of their day to feed your new immobile flesh sack. Something you can automate with a paste dispenser if the prisoner can still move around.
You don't need to cut of their legs and arms.
biotech, dead calm gene...
poof, a docile prisoner that will never rebel, can feed them self (if allowed to) and can be all sorts of usefull with the right combination of other DLCs and mods.
though... i believe the thick layer of dust that is in this topic means that OP either got their questions answered a long time ago or they simply forgot about the topic.